Agios Nikolaos is the capital town of Lassithi. Here, the bottomless Salt Lake Voulismeni dominates the area. A narrow channel of water connects the lake with the sea, while an imposing backdrop of red rock and trees adds to the natural beauty of the scenery.

The city boasts interesting Archaeological, Folklore, and Natural History museums, Byzantine churches, a well-organized marina, bustling pedestrian streets, and traditional squares with buzzing cafés and restaurants.